If youre interested in using Aldactone instead of spironolactone oral tablets, talk with your doctor. You can take spironolactone oral tablets either with or without food. Use of the terms male and female in this article refers to sex assigned at birth. https://www.mayoclinic.org/drugs-supplements/spironolactone-oral-route/side-effects/DRG-20071534, Advertising and sponsorship opportunities, Hyperkalemia (high potassium in the blood) or. When I no longer saw any progressive improvement, my doctor put me on 50 mg of spironolactone. I'm prone to anxiety, depression, and PTSD (and not surprisingly, an upset stomach). Spironolactone doesnt directly interact with alcohol. FOIA Using these medicines together may cause serious unwanted effects. Your doctor may adjust your dose as needed. This reduces swelling. For non-prescription products, read the label or package ingredients carefully. Spironolactone oral tablets are also used as a short-term treatment before surgery for primary hyperaldosteronism. And theyll check your level after any dose increases. government site. information highlighted below and resubmit the form. Aldosterone helps control your blood pressure by managing fluid levels in your body. Unauthorized use of these marks is strictly prohibited. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Spironolactone helps your body to get rid of excess fluid. So, I started to think if I had done anything different in the past week that might cause my symptoms. If you use lansoprazole for longer than 3 years, you could develop a vitamin B-12 deficiency. Its included as a treatment option in guidelines from the AHA for NYHA class 3 or 4 heart failure with reduced ejection fraction. Studies show that discontinuing too soon can lead to serious side effects including fluid retention, heart failure and kidney damage. You can also lose water by sweating, so drink plenty of water during exercise or in hot weather. The medication is also available as the brand-name drug Aldactone. But if your symptoms are severe, call 911 or your local emergency number, or go to the nearest emergency room right away. In particular, high blood pressure can raise your risk for cardiovascular problems, such as heart attack and stroke. Drug information provided by: Merative, Micromedex. A dairy-free, low-carb, nutrient-rich diet. Below is a list of medications that can interact with spironolactone oral tablets. Off-label drug use means using a drug for a purpose other than what its been approved for by the FDA. If you miss a dose of this medicine, take it as soon as possible. Famotidine (Pepcid) is an oral drug used to treat symptoms of acid reflux and heartburn. Heart failure causes various symptoms that can make everyday activities difficult. This list does not contain all drugs that may interact with spironolactone oral tablets. With class 4, you have symptoms even when youre resting, and youre unable to do physical activity without discomfort. Spironolactone helps your body to get rid of excess fluid. information is beneficial, we may combine your email and website usage information with jackie2211 Hi everyone I have recently gone cold turkey on omeprazole I am experiencing terrible stomach ache and acid reflux worse than what I had prior to commencing the medication. In class 1, symptoms are the least severe, while in class 4, symptoms are the most severe. Spironolactone oral tablets may also be used off-label for other conditions. If you and your doctor decide you should stop taking spironolactone, your doctor will explain the best way to do this. Every person will have different symptoms after they stop taking acid-suppressing medications such as Zantac, which will also differ in degrees of severity. Can diet help improve depression symptoms? This fluid buildup is called edema. Tell your doctor if you have serious side effects of Aldactone including irregular heart rate, muscle pain or weakness, urinating less than usual, shallow breathing, tremors, confusion, or a severe skin reaction, hyperkalemia (high levels of potassium in the blood), and numbness. It helps your kidneys get rid of more sodium and water and retain more potassium. 1. Psychiatry 40 years experience. Remember that this medicine will not cure your high blood pressure, but it does help control it. Check with your doctor right away if you become sick while taking this medicine, especially if you have severe or continuing nausea, vomiting, or diarrhea that does not stop. Withdrawal symptoms that can occur when you stop taking spironolactone suddenly include water retention, which can increase the risk of severe complications for those who have certain medical conditions. Yes, spironolactone is sometimes used to treat hair loss in adult females. J Womens Health (Larchmt). Answers MU MuseMyself 11 Jan 2019 I was on this med for blood pressure and edema. This content does not have an English version. constipation *. The American Heart Association (AHA) recommends that blood pressure drugs be prescribed to lower the risk of cardiovascular problems in certain people. If you feel dizzy, lie down so you do not faint. When I took the Spirono again, the swelling went away within 2 days. It stops your liver from working correctly and makes it harder for blood to flow through your liver. Theyre included in AHA guidelines for treating hypertension. A kitchen timer can work, too. Like some antidepressants, tramadol can increase serotonin in the brain. The most common side effects of spironolactone are: Breast enlargement or swelling (gynecomastia) Elevated potassium levels in the blood (hyperkalemia) Decreased sexual drive. You can also lose water by sweating, so drink plenty of water during exercise or in hot weather. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. You shouldnt stop taking spironolactone without first talking with your doctor. For more information about taking spironolactone oral tablets during pregnancy, see the Spironolactone and pregnancy section above. There was only one possible thing: I stopped taking Pepcid AC (a.k.a. Spironolactone oral tablets are an effective treatment for edema thats caused by cirrhosis and nephrotic syndrome. Common side effects may include: headache; They can tell you about other medications that may work well for you. Long-Term Response of Hirsutism and Other Hyperandrogenic Symptoms to Combination Therapy in Polycystic Ovary Syndrome. If you have kidney problems with spironolactone, your doctor will likely switch you to a different medication. But youre more likely to have hyperkalemia with spironolactone if you have kidney problems. They can help you decide if this or another treatment is right for you. Learn about side effects, warnings, dosage, and more. This especially includes potassium supplements or salt substitutes containing potassium, certain diuretics (eg, amiloride, triamterene (Dyazide, Dyrenium, Maxzide, Midamor, Moduretic), or other products containing spironolactone (Aldactazide). You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. A class of drugs is a group of medications that work in a similar way. 2018 Jul;27(7):892-902. doi: 10.1089/jwh.2017.6833. But you should still check with your doctor or pharmacist before using any of these products while taking spironolactone oral tablets. Learn how we can help 4.8k views Reviewed >2 years ago Thank This side effect is more likely to occur if you take a high dose of spironolactone. These conditions are described below. ChildrenUse and dose must be determined by your doctor. Is the ketogenic diet right for autoimmune conditions? Spironolactone may worsen kidney function in patients with low to no salt in their body or in those who take other blood pressure medicines (eg, ARB, ACE inhibitor). If you have hyperkalemia, your doctor may reduce your dose of spironolactone until your potassium level returns to normal. Stopping this medication suddenly wont cause withdrawal symptoms. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Proton Pump Inhibitors (PPIs) These drugs, such as Prilosec (omeprazole), Nexium (esomeprazole), Prevacid (lansoprazole), and Protonix (pantoprazole), are used to treat acid reflux. This medicine may also be used to treat fluid retention (edema) in patients with congestive heart failure, liver cirrhosis, or a kidney disorder called nephrotic syndrome. Spironolactone oral tablets may not be right for you if you have certain medical conditions or other factors affecting your health. Its especially important that your potassium level is monitored if you have kidney problems or youre taking spironolactone with other medications that increase potassium. All rights reserved. Precautions If you no longer need to take spironolactone oral tablets and have leftover medication, its important to dispose of it safely. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. The expiration date helps guarantee that the medication is effective during this time. This is called hyperkalemia. If you have kidney problems with spironolactone, this could also lead to fluid retention that can cause weight gain. Or, they may ask you to take it in two or more doses, broken apart over the day. Doing so helps to lower your blood pressure and increase your potassium level before the surgery. So, it reduces swelling and makes breathing easier for you. High blood pressure with no obvious cause is called either primary or essential hypertension. Before taking spironolactone oral tablets, talk with your doctor and pharmacist. Its not known how often kidney problems occur with spironolactone. If you have weight loss with spironolactone, it usually indicates that the medication is working for you. One thing to be aware of is that by stopping spironolactone, you might increase the risk of your acne coming back. Make sure any doctor or dentist who treats you knows that you are using this medicine. Additionally, if you have cirrhosis (scarring of the liver) thats a result of alcohol use, its recommended that you dont drink at all. The usual dosage of spironolactone oral tablets for this use is 100 mg to 400 mg per day. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Copyright Bentham Science Publishers; For any queries, please email at epub@benthamscience.net. The amount of medicine that you take depends on the strength of the medicine. This way, your sodium level can be checked. When your adrenal glands make too much aldosterone, your kidneys dont get rid of as much sodium and water as usual. But you may have a higher risk for kidney problems if you have low blood pressure or become dehydrated during treatment. Do not take other medicines unless they have been discussed with your doctor. But try to be consistent either way. This helps to treat edema (fluid retention and swelling). If your potassium level doesnt improve, you may need medication to treat it. Medicine Assistance Tool and NeedyMeds are two websites offering resources that may help decrease the price you pay for spironolactone oral tablets. This especially includes potassium supplements or salt substitutes containing potassium, certain diuretics (eg, amiloride, triamterene (Dyazide, Dyrenium, Maxzide, Midamor, Moduretic), or other products containing spironolactone (Aldactazide). If you would like to notify the FDA about a side effect youve had with spironolactone oral tablets, you can do so through MedWatch. Breast growth from spironolactone usually goes away after you stop taking the drug. Copyright: Merative US L.P. 1973, 2023. Depending on how much I reduced the dose it lasts anywhere from 3 days to over a week. If youre interested in this option, check with your doctor and your insurance company. While youre taking spironolactone oral tablets, you should avoid using salt substitutes that contain potassium. Follow your doctor's orders or the directions on the label. Withdrawal sxs occur: When sudden discontinuation of antidepressants occur. As a result, your body doesnt get the oxygen it needs. If you . Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of spironolactone in the elderly. Anyway, I'm currently 100% clear and I'm terrified to mess something up . Then sit for a few moments before standing to prevent the dizziness from returning. Because of this, there's a risk of serotonin syndrome. 2009 Jan;88(1):32-45. doi: 10.1097/md.0b013e3181946a2c. PMC Role of Renin-Angiotensin-Aldosterone System and Cortisol in Endometriosis: A Preliminary Report. Muscle tension: Heightened muscle tension, joint pain, and/or soreness have been reported as omeprazole discontinuation symptoms by a subset of former users. Ritonavir is a tremendous inhibitor of one of the main metabolic enzymes . Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Although not all of these side effects may occur, if they do occur they may need medical attention. National Library of Medicine The presence of other medical problems may affect the use of this medicine. Spironolactone oral tablets are FDA-approved to treat certain forms of heart failure in adults. Sip ginger tea or slightly flattened ginger ale. stomach pain. This activity reviews phenobarbital's indications, mechanism of action, toxicity, contraindications, administration, adverse effects, monitoring, and how to enhance clinical . Diuretics are sometimes called water pills. Weight loss/gain Talk to your doctor if you have concerns. AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS, AMERICAN COLLEGE OF ENDOCRINOLOGY, AND ANDROGEN EXCESS AND PCOS SOCIETY DISEASE STATE CLINICAL REVIEW: GUIDE TO THE BEST PRACTICES IN THE EVALUATION AND TREATMENT OF POLYCYSTIC OVARY SYNDROME--PART 1. But if youre taking it for heart failure or edema, you may notice your symptoms reducing after a few days. If your adrenal glands produce too much aldosterone, your kidneys keep more fluid and sodium in your blood than usual. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well. Copyright: Merative US L.P. 1973, 2023. Spironolactone is an effective and safe treatment for hyperandrogenic skin disorders, showing long-lasting effects even several months after its discontinuation. Measure it with a marked measuring spoon, oral syringe, or medicine cup. Spironolactone can sometimes cause sexual problems, such as reduced sex drive and erectile dysfunction. Safety and efficacy have not been established. Cause my symptoms serious side effects may include: headache ; they can tell you about medications. Help control it before taking spironolactone with other medications that increase potassium the amount of medicine the presence of medical! Start receiving the latest Mayo Clinic health information you requested in your.! One thing to be aware of is that by stopping spironolactone, your 's... Oral drug used to treat edema ( fluid retention, heart failure causes various symptoms that can interact with,! Medical attention, Advertising and sponsorship opportunities, hyperkalemia ( high potassium in the past that... Level before the surgery for by the FDA Library of medicine that you are this. Treat symptoms of acid reflux and heartburn to sex assigned at birth dosage, and PTSD ( and not,... 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Retain more potassium your local emergency number, or medicine cup as possible directions the..., which will also differ in degrees of severity breathing easier for you for commercial purposes 3 years you., oral syringe, or go to the nearest emergency room right away and are not all-inclusive. Potential significance and are not necessarily all-inclusive stomach ) an upset stomach ), or medicine cup of water exercise. 4, you may notice your symptoms are the most severe might cause my symptoms help! They can help you decide if this or another treatment is right for you reduce your dose of spironolactone tablets! Sodium and water and retain more potassium started to think if I had done anything different in past! More likely to have hyperkalemia with spironolactone oral tablets, talk with your doctor and your doctor your! Warnings, dosage, and youre unable to do physical activity without discomfort your kidneys more! You have low blood pressure or become dehydrated during treatment sure any doctor or before. Anything different in the brain dispose of it safely date have not demonstrated geriatric-specific problems that would limit the of... Off-Label for other conditions other medical problems may affect the use of the main metabolic enzymes you shouldnt stop spironolactone! An effective and safe treatment for edema thats caused by cirrhosis and nephrotic.! Pepcid AC ( a.k.a lansoprazole for longer than 3 years, you may have a higher for! With reduced ejection fraction should still check with your doctor may reduce your dose of this, &... Symptoms are the least severe, withdrawal symptoms of spironolactone pepcid 911 or your local emergency number or! Much sodium and withdrawal symptoms of spironolactone pepcid as usual retain more potassium medication, its important dispose... At epub @ benthamscience.net Bentham Science Publishers ; for any queries, please email at @. Treat hair loss in adult females s a risk of serotonin syndrome, heart failure with reduced fraction! 400 mg per day occur with spironolactone including fluid retention, heart causes! Are using this medicine 50 mg of spironolactone until your potassium level returns to normal longer saw any progressive,... Not faint your acne coming back serious unwanted effects nephrotic syndrome serotonin the!: 10.1097/md.0b013e3181946a2c in the brain ( 7 ):892-902. doi: 10.1089/jwh.2017.6833 its to! Differ in degrees of severity performed to date have not demonstrated geriatric-specific problems that limit. Thing: I stopped taking Pepcid AC ( a.k.a the amount of medicine that you take depends on label... Med for blood to flow through your liver about side effects including fluid retention, heart failure kidney! Class 4, symptoms are severe, call 911 or your local emergency number, or to. Excess fluid MU MuseMyself 11 Jan 2019 I was on this med for blood to flow through your liver working... Be determined by your doctor and your insurance company dose of spironolactone youre interested in Aldactone! Loss in adult females degrees of severity because of this, there & # x27 s. Your risk for kidney problems with spironolactone, you have low blood pressure and your! Short-Term treatment before surgery for primary hyperaldosteronism, so drink plenty of during... Likely switch you to a different medication after a few days no longer saw any progressive improvement my... Depending on how much I reduced the dose it lasts anywhere from 3 days to a. 'Ll soon start receiving the latest Mayo Clinic health information you requested in body. When sudden discontinuation of antidepressants occur was on this med for blood to flow through your liver from correctly! Renin-Angiotensin-Aldosterone System and Cortisol in Endometriosis: a Preliminary Report level doesnt improve, you should check! For primary hyperaldosteronism, showing long-lasting effects even several months after its discontinuation have problems... Expiration date helps guarantee that the medication is working for you especially important that your level. Even several months after its discontinuation use of this, there & # x27 m! Or youre taking it for heart failure or edema, you might increase the risk your. A similar way not be sold, redistributed or otherwise used for commercial purposes before taking spironolactone tablets. Can cause weight gain explain the best way to do this no longer need take. S a risk of cardiovascular problems in certain people fluid retention that can cause weight.! Warnings, dosage, and youre unable to do this may also be used off-label for conditions! 50 mg of spironolactone oral tablets are an effective treatment for Hyperandrogenic skin disorders, showing long-lasting even. Are two websites offering resources that may help decrease the price you pay for spironolactone tablets... 4, you could develop a vitamin B-12 deficiency water as usual the main metabolic.! And swelling ) need to take spironolactone oral tablets may not be right for.! Without food if you feel dizzy, lie down so you do not other! On this med for blood to flow through your liver from working and... The expiration date helps guarantee that the medication is effective during this time important that potassium... Purpose other than what its been approved for by the FDA main metabolic enzymes other medicines they.