Various studies on honokiol support the use of this polyphenol in magnolia bark as a therapy for cancer treatment and prevention. Its one of the top stress relievers out there. Yet again, clinical studies in humans need to be conducted. Although there isnt much historical information on the magnolia tree and magnolia bark in Asia, there were sightings of the tree in North Carolina as early as the 16th century. In addition to this, the mice spent more time in deep sleep resulting in an overall higher quality of sleep. Magnolia bark extract has been tested in studies as an ingredient in chewing gum. For example, because magnolia bark supplements may promote sleep in some individuals, its probably best not to take the supplements in combination with any other type of sedative or sleeping pill. The Journal of pharmacy and pharmacology, 51(1), 97103. Research shows that magnolia bark benefits sleep quality. British journal of pharmacology, 167(3), 587598. It stays on ready alert around the clock and never gets to stand down. (2018). It combines excellent craftsmanship in traditional Chinese wellness therapy: Chinese full body massage, foot massage. When cortisol levels decrease, it suggests that overall stress has also decreased. The extract was able to regulate protein levels in the brain that are indicative of anxious behavior. Think I might pick up some lemon balm now though haven't . Our website services, content, and products are for informational purposes only. Polyphenols are highly valued for their antioxidant levels and believed to offer many health benefits. Again, note that magnolia bark extract was not the only supplement given in this study. Skip to content Resources Articles Body Systems Cancer Solutions Cardiovascular Health Digestive Health Immune System Breast Health It also helps reduce brain inflammation, which has been closely linked with depression, anxiety, and other mood disorders. Those gentle detox abilities make it easier for your body to cope with other challenges, including chronic stress. Scientific reports, 7, 45342. https://doi.org/10.1038/srep45342, Groves, Maria Noel, RH (AHG). Magnolia bark has a sedative effect on the body and has been used to promote sleep and ease anxiety. Modified Citrus Pectin Formula - Dr. Isaac Eliaz The most advanced and effective solution for health, aging and longevityClinically Researched Modified Citrus Pectin. Getting adequate amounts of deep sleep is key for mental and physical health. Research shows that a number of healthy stress relief strategies, including those listed below, also offer protection against Alzheimers and other forms of cognitive decline. OncoTargets and therapy, 11, 52195226. Not recommended for use during pregnancy and breastfeeding due to lack of data and evidence. Here are 15 effective ways to relieve stress and anxiety. A mixture of honokiol and magnolol at 20 and 40 mg/kg inhibited stress-induced decreases of serotonin in the frontal cortex, hippocampus, striatum, hypothalamus, and nucleus accumbens in mice. California Sycamore. (2000). There are many different methods and techniques, so keep trying until you find a practice you feel good about. Many benefits of magnolia bark can be attributed to two powerful polyphenols magnolol and honokiol. Last medically reviewed on April 7, 2020, Cissus quadrangularis is a plant that has long been used as a natural remedy to treat a wide variety of ailments. Those who practice traditional Chinese medicine (TCM) often harvest the bark in April and June. In fact, magnolia bark is thought to be one of the best herbs for sleep. Magnolia bark extract can be found at most supplement retailers. are clickable links to these studies. Sold by Swanson Health Products and ships from Amazon Fulfillment. Nevertheless, additional research in humans is needed. The first one is called Banxia Houpo Tang (Chinese) is a formula that helps move stagnant qi in the throat, head, and solar plexus area. An in vitro and in vivo study discovered that honokiol inhibits breast cancer cells from growing and could boost the effects of other drugs used against breast cancer. Along with these health benefits, the bark also has strong potential for weight loss, reducing inflammation, and improving sleep. Thats when survival mode transforms into a threat on its own. 220 A.D.). Its other names are magnolia cortex, cucumber tree, honoki, and swamp sassafras. https://www.ncbi.nlm.nih.gov/books/NBK537103/, Park, I., Oh, S., Lillehoj, E. P., & Lillehoj, H. S. (2020). Therefore, the effects cannot be credited to the tree bark alone. Magnolol and honokiol achieve this effect by improving the intestinal movement that helps move digested food through the gastrointestinal tract. out of DrWeil.com subscriptions at any time. Over-the-Counter Sleep Aids With over 50 published studies and counting, researchers at Harvard, the NIH and other renowned institutes are increasingly interested in the singular ability of this MCP to halt and reverse the devastating actions of galectin-3, in cancer as well as heart disease, kidney failure, arthritis and much more. Modern research shows that magnolia bark has anti-inflammatory, antioxidant, stress, and weight-reducing effects. Magnolia bark for anxiety. Magnolol exerts anticancer activity in hepatocellular carcinoma cells through regulating endoplasmic reticulum stress-mediated apoptotic signaling. Use a combination of these stress-reducing methods to calm down your mind and body no matter what life throws at you. Magnolia essential oil is known for stimulating the lymphatic system and helps in making the liver to function properly and help in toxins elimination. Moreover, studies in both test tubes and living organisms have demonstrated that magnolia bark extract has no mutagenic or genotoxic properties, meaning theres a low risk of magnolia bark causing genetic mutations (1). are clickable links to these studies. Retrieved from: https://www.henriettes-herb.com/eclectic/dmna/magnolia.html#glau-bot-hist, Ge, L., Zhang, W., Zhou, G., Ma, B., Mo, Q., Chen, Y., & Wang, Y. That inflammation reaction is a key way that chronic stress leads to serious mood disorders such as anxiety and depression. Exclusive Lifestyle, Nutrition & Health Advice. Cissus quadrangularis: Uses, Benefits, Side Effects, and Dosage, Galangal Root: Benefits, Uses, and Side Effects. Magnolia bark has been used for centuries to treat digestive problems, including nausea, abdominal pain and bloating, diarrhea, and loss of appetite. Modified Citrus Pectin (MCP): When it comes to supplements that reduce the effects of stress, clinically researched modified citrus pectin (MCP) doesnt usually make the list but it should. Honokiol: When stress and anxiety overwhelm your mind and your life, honokiol a compound extracted from magnolia bark offers quick, calming relief. BioMed research international, 2021, 6688414. https://doi.org/10.1155/2021/6688414, Wang, Y. D., Sun, X. J., Yang, W. J., Li, J., & Yin, J. J. The bark of the magnolia . The bark and flowers are used in Traditional Chinese Medicine. Frontiers in veterinary science, 7, 157. https://doi.org/10.3389/fvets.2020.00157, Poivre, M., & Duez, P. (2017). Breitenbush, OR. Some researchers believe that these effects are due to honokiol, a natural compound in the bark. Liposomal honokiol, a potent anti-angiogenesis agent, in combination with radiotherapy produces a synergistic antitumor efficacy without increasing toxicity. A study in mice found a magnolol dose of 2.30.9 mg per pound (525 mg per kg) of body weight significantly decreased sleep latency, or the amount of time it takes to fall asleep (27). This is why I use meditation as an integral part of my medical and healing practice. In a 2016 review, magnolia bark was found to improve high blood sugar levels and diabetic complications in animals (15). It Starts in the Kitchen, Acid Reflux Diet: Best Foods, Foods to Avoid & Supplements that Help, Black Mold Symptoms + 12 Natural Remedies, Traditional Chinese Medicine Benefits, Herbs & Therapies, Chronic low-level inflammation, which can be triggered by high levels of a, Difficulty learning and retaining new information. It contains berberine. Typically, magnolia bark is bark of the houpo magnolia tree that has been stripped away from it branches and stems to make supplements. bark extract possesses anxiolytic-like activity with neuroprotective effect through the modulation of CB1 receptor. or Healthy Lifestyle Brands. Cancer acts with innate intelligence, like it has a mind of its own, and uses sophisticated mechanisms to survive at any cost. Unfortunately, you cant avoid stress completely. The more effectively you cope with stress today, the healthier youll be for the rest of your life. Our team aims to be not only thorough with its research, but also objective and unbiased. Here are some notable sorrel. What Is Elecampane Root, and Does It Have Benefits? 4 But in this study, pine pollen was combined with metformin, a drug that can cause those side effects. The magnolia extract improved health issues such as anxiety, insomnia, depression, and libido. In this article, we will look at the health benefits of magnolia bark, its safety, and its history. Magnolia bark extract is readily available in pill form. Nine phenylethanoid glycosides from Magnolia officinalis var. The polyphenols in magnolia bark honokiol and magnolol have been found to help induce and improve sleep. Cancer statistics, 2020. These findings might lead. The bark is slightly decocted, steamed, and then rolled and dried once the color is purple-brown. This article reviews galangal root's benefits and safety, as well as how it, Elecampane root is a folk medicine that may have several health benefits. 3 Supplements To Consider. Most of this research is still in the basic science stage, but an Italian study published in February, 2011, compared a magnolia bark extract to soy isoflavones for treatment of anxiety, irritability and insomnia in menopausal women. These various health benefits are attributed to magnolol and honokiol, two phenolic compounds present in magnolia bark. It is the most effective treatment I know. My mission is to provide a holistic approach to health and wellness, and bringing balance to the min Kuribara, H., Kishi, E., Hattori, N., Okada, M., & Maruyama, Y. Currently, magnolia bark is widely used in food supplements and beauty products.You can also find the bark's name listed in the American Pharmacopeia as a bitter antimalarial tonic. Some of the benefits of magnolia bark, such as improved sleep and mood, could be especially beneficial for women during menopause (30). It's most well-known for boosting liver function and helping with adrenal functions, but other benefits also include: acting like a powerful brain tonic (improving focus, concentration, memory and mental energy) improving digestion supporting hormonal balance nourishing the skin When the danger passes, the system turns off and resets. Zhang, W. W., Li, Y., Wang, X. Q., Tian, F., Cao, H., Wang, M. W., & Sun, Q. S. (2005). Exceeding the recommended daily limit of magnesium can lead to diarrhea, nausea, stomach cramps, and heart problems. Healthy eating: When youre feeling stressed, your instinct may be to grab for sweet, salty, fatty foods but those can add to your bodys stress load. Dietary Supplementation With Magnolia Bark Extract Alters Chicken Intestinal Metabolite Levels. 2011-2022 Examine.com Inc. Privacy Policy | Terms of Service. Its important to note that the exact mechanisms through which the isolated compounds contribute to these effects are still being investigated. The Therapeutic Effects of Magnolia Officinalis Extraction on an Antibiotics-Induced Intestinal Dysbacteriosis in Mice. All rights reserved. The second formula, called Saiboku-To (Japanese) is a formula that is said to reduce asthma symptoms through its anti-inflammatory properties. Consider alternative sleep herbs that are harvested in a more sustainable manner. Furthermore, honokiol may not only have anticancer properties itself but also help increase the effectiveness of other anticancer and radiation drug therapies (18, 19). The bark, leaves, and flowers of the houpo magnolia tree are used in traditional medicine to treat anxiety, depression, and more. In a recent animal study, Magnolia officinalis extract improved and normalized levels of gut bacteria in mice. Although commonly found in traditional Chinese and Japanese medicine, magnolia bark was also traditionally used in Native American medicine. Read on for proven tactics. The magnolia is a deciduous tree that has multiple species that are native to eastern Asia, as well as the Americas. Coping with stress is a full-time job, and your body needs all the support it can get. At the same time, fascinating research continues to unravel the vast network of mechanisms that connect our mind and emotions to our physical health. biloba fruits and their protective effects against free radical-induced oxidative damage. Retrieved from: https://www.christopherhobbs.com/webdocs/class-handouts/various/Healing-Sleep-Breitenbush.pdf, Hu, J., Chen, L. J., Liu, L., Chen, X., Chen, P. L., Yang, G., Hou, W. L., Tang, M. H., Zhang, F., Wang, X. H., Zhao, X., & Wei, Y. Q. It can even change the way your body manages stress, making it much harder to break the stress cycle. As an integrative MD and researcher, licensed acupuncturist and life-long practitioner of Buddhist meditation, Ive developed a unique perspective and methodology around mind-body medicine, and specifically, our innate abilities to heal ourselves and others. One type Magnolia officinalis is commonly called the houpo magnolia, or sometimes simply magnolia bark.. https://doi.org/10.3322/caac.21590, Talbott, S. M., Talbott, J. For digestive problems, magnolia bark. (2020). Traditional Chinese Medicine (TCM) is an ancient form of healthcare that dates the guardian of the tumor microenvironment, Amitabha Medical Clinic and Healing Center, Frankincense Essential Oil Uses and Benefits for Healing, Oregano Oil Benefits for Infections, Fungus & Even the Common Cold, L-Glutamine Benefits Leaky Gut & Metabolism, Secret Detox Drink Recipe (A Natural Detox Drink Recipe), Chia Seeds Benefits: The Omega-3, Protein-Packed Superfood, Apple Cider Vinegar Benefits for Weight Loss, Skin Health, Cholesterol & More, Symptoms of Candida Overgrowth & How to Get Rid of It, Investing in Your Grandkids Future? Some chemicals in phellodendron might reduce redness and swelling. In vitro and animal data. Research shows that both magnolol and honokiol are, by nature: The extract of the magnolia bark has been used for thousands of years in traditional Chinese and Japanese medicine. Honokiol was found to reduce anxiety levels in the mice without slowing down motor functions. It is also commonly used to support gastrointestinal health. , Additionally, since one use of magnolia bark is to help in sleeping, you should not take it alongside other anti-anxiety drugs or sleeping pills. Neolignans are a type of polyphenol micronutrient in plants. A second study in mice observed similar outcomes after administering honokiol, which also decreased the amount of time it took the mice to fall asleep and transition into non-REM sleep (28). Below are the top researched-backed magnolia bark benefits for health. In fact, eye-opening research shows a direct link between galectin-3 and depression, making this alarm protein a strong potential target in treating stress-related mental illness. Magnolia bark has been known to have a wide therapeutic scope, being especially supportive for anxiety and stress, and gastrointestinal issues. Grandchildren are some of lifes greatest treasures. The scientific name of magnolia bark is Magnolia officinalis.The Chinese also call this herb "Houpu" referring to the thick (hou) bark that comes from the unadorned (pu) part of the tree. CA: a cancer journal for clinicians, 70(1), 730. Magnolia bark is an unapproved substance without clinical data to back up the claims of traditional practitioners. Thus, it cannot be said with certainty that the effects were due solely to the magnolia bark. An animal study utilizing Magnolia officinalis bark extract proved to reduce anxiety while having a neuroprotective effect. Another study in 180 menopausal women determined that a supplement containing magnolia bark, soy isoflavones, and lactobacilli more effectively reduced the severity and frequency of hot flashes than a supplement containing the soy isoflavones alone (33). Exercise: Physical activity helps your body blow off steam, but its benefits dont stop there. The goal is to eliminate the disease and simultaneously restore health, and in my decades of research and working with patients, Ive seen many outcomes that other doctors would call miraculous. We call it simply, integrative medicine. The supplement can be found at many online and retail stores. Retrieved from: https://static1.squarespace.com/static/55636a78e4b0658666cb6541/t/5eac6913be207478cdbd2980/1588357463831/Perky+Calm+Alert+Slides.pdf, Ogobuiro I, Gonzales J, Tuma F. (2021) Physiology, Gastrointestinal. Chronic stress takes a huge toll on your physical health. Magnolia bark has been used in traditional Japanese and Chinese medicine for thousands of years.